Browsing by Author "de Miguel, Rosa"

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    Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data
    (2021-08) Díaz, Natalia A; de Miguel, Rosa; Agüero, Fernando; Sued, Omar; Arribas, José R; Ambriosioni, Juan; Hospital Clinic COVID-19 in HIV Investigators
    The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.