Clinical challenges in HIV/AIDS: Hints for advancing prevention and patient management strategies
Date
2016-8
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Acquired immune deficiency syndrome has been one of the most devastating epidemics of the last century. The current estimate for people living with the HIV is 36.9 million. Today, despite availability of potent and safe drugs for effective treatment, lifelong therapy is required for preventing HIV re-emergence from a pool of latently infected cells. However, recent evidence show the importance to expand HIV testing, to offer antiretroviral treatment to all infected individuals, and to ensure retention through all the cascade of care. In addition, circumcision, pre-exposure prophylaxis, and other biomedical tools are now available for included in a comprehensive preventive package. Use of all the available tools might allow cutting the HIV transmission in 2030. In this article, we review the status of the epidemic, the latest advances in prevention and treatment, the concept of treatment as prevention and the challenges and opportunities for the HIV cure agenda.
Description
Keywords
Clinical Challenges, Prevention, Management Strategies
Citation
Omar Sued, María Inés Figueroa, Pedro Cahn, Clinical challenges in HIV/AIDS: Hints for advancing prevention and patient management strategies, Advanced Drug Delivery Reviews, Volume 103, 2016, Pages 5-19, ISSN 0169-409X,