The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital

Files

v40n6a09-448-54.pdf (1.7 MB)

Date

2016-12

Authors

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Objective: To determine rates of retention, antiretroviral therapy (ART) use, and viral suppression in an adult cohort from a public tertiary referral hospital in the city of Buenos Aires, Argentina. Methods: HIV-positive ART-naïve patients ≥ 18 years old starting care 2011-2013 contributed data until the end of 2014. Three outcomes were assessed in 2014: retention in care, ART use, and viral suppression. Patient characteristics associated with each outcome were assessed through logistic regression. Results: A total of 1 031 patients were included. By the end of 2014, 1.5% had died and 14.8% were transferred to a different center. Of the remaining 859 patients, 563 (65.5%) were retained in 2014. Among those retained, 459 (81.5%) were on ART in 2014. Of those 459 on ART, 270 (58.8%) were virologically suppressed. Younger age was associated with lower retention (OR (odds ratio): 0.67; 95% CI (confidence interval): 0.44-0.92 for ≥ 35 vs. < 35 years), but unrelated with ART use or viral suppression. Low CD4 count at first visit was associated with ART use (OR: 35.72 for CD4 < 200, 7.13 for CD4 200-499 vs. ≥ 500, P < 0.001) and with virologic suppression (OR: 2.17 for CD4 < 200, 2.46 for CD4 200-499 vs. ≥ 500, P: 0.023). Conclusions: Our hospital in Buenos Aires is still below the recommended 90-90-90 targets of the Joint United Nations Programme on HIV/AIDS (UNAIDS) for ART use and viral suppression. We found a major gap in retention in care. Identifying younger age as being associated with worse retention will help in the design of targeted interventions.

Description

Fil: Cesar C. Fundación Huésped, Buenos Aires; Argentina
Fil: Sued O. Fundación Huésped, Buenos Aires; Argentina
Fil: Fink V. Fundación Huésped, Buenos Aires; Argentina
Fil: Yamamoto C. Fundación Huésped, Buenos Aires; Argentina
Fil: Cahn P. Fundación Huésped, Buenos Aires; Argentina

Keywords

HIV, Argentina

Citation

URI

https://repositorio.huesped.org.ar/handle/123456789/1420

Collections

Articulos científicos