Asking the right questions: developing evidence-based strategies for treating HIV in women and children

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dc.contributor.authorKarim, Quarraisha A.
dc.contributor.authorBanegura, Antoine
dc.contributor.authorCahn, Pedro
dc.contributor.authorChristie, Charmagne D.
dc.contributor.authorDintruff, Robin
dc.contributor.authorDistel, Michael
dc.contributor.authorHankins, Catherine
dc.contributor.authorHellmann, Nicholas
dc.contributor.authorKatabira, Elly
dc.contributor.authorLehrman, Sandra
dc.contributor.authorMontaner, Julio
dc.contributor.authorPurdon, Scott
dc.contributor.authorRooney, James F.
dc.contributor.authorWoof, Robin
dc.contributor.authorHeidari, Shirin
dc.date.accessioned2024-05-23T18:53:33Z
dc.date.available2024-05-23T18:53:33Z
dc.date.issued2011
dc.description.abstractIn July 2010, the World Health Organization (WHO) issued formal revisions of its guidelines on the use of highly active antiretroviral therapy for HIV. The new guidelines greatly expand eligibility for treatment of adults and children, as well as for pregnant women seeking prophylaxis for vertical HIV transmission. WHO's new recommendations bring the guidelines closer to practices in developed countries, and its shift to earlier treatment alone will increase the number of treatment-eligible people by 50% or more. Scaling up access to HIV treatment is revealing important gaps in our understanding of how best to provide for all those in need. This knowledge gap is especially significant in developing countries, where women and children comprise a majority of those living with HIV infection. Given the magnitude and significance of these populations, the International AIDS Society, through its Industry Liaison Forum, prioritized HIV treatment and prophylaxis of women and children. In March 2010, the International AIDS Society and 15 partners launched a Consensus Statement outlining priority areas in which a relative lack of knowledge impedes delivery of optimal prevention of mother to child transmission (PMTCT) and treatment to women and children. The Consensus Statement, "Asking the Right Questions: Advancing an HIV Research Agenda for Women and Children", makes a special appeal for a more gender-sensitive approach to HIV research at all stages, from conception to design and implementation. It particularly emphasizes research to enhance the understanding of sex-based differences and paediatric needs in treatment uptake and response. In addition to clinical issues, the statement focuses on programmatic research that facilitates access and adherence to antiretroviral regimens. Better coordination of HIV management with sexual and reproductive healthcare delivery is one such approach. We discuss here our knowledge gaps concerning effective, safe PMTCT and treatment for women and children in light of the expansion envisioned by WHO's revised guidelines. The guideline's new goals present an opportunity for advancing the women and children's agenda outlined in the Consensus Statement.
dc.identifier.citationKarim, Q. A., Banegura, A., Cahn, P., Christie, C. D., Dintruff, R., Distel, M., ... Heidari, S. (2011). Asking the right questions: Developing evidence-based strategies for treating HIV in women and children. BMC Public Health.
dc.identifier.otherDOI: 10.1186/1471-2458-11-388
dc.identifier.urihttps://repositorio.huesped.org.ar/handle/123456789/1090
dc.relation.ispartofseriesBMC Public Health
dc.subjectEvidence-based strategies
dc.subjecttreating HIV
dc.subjectwomen and children
dc.titleAsking the right questions: developing evidence-based strategies for treating HIV in women and children

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