Rubione, JulietaDuette, GabrielaPerez, PaulaPereyra Gerber, PabloSalido, JorgeCagnoni, AnaGuzman, LauraAdamczyk, ArielSued, OmarGhiglione, YaninaLaufer, NataliaMariƱo, KarinaRabinovich, GabrielOstrowski, Mario2024-05-212024-05-212019Journal of Virus Eradication 5:10-11. DOI: 10.1016/S2055-6640(20)31039-610.1016/S2055-6640(20)31039-6https://repositorio.huesped.org.ar/handle/123456789/1007HIV-positive individuals on antiretroviral therapy(art) have detectable cell-associated unspliced (ca-Us) HIV rNain cD4+ t-cells from blood which varies with time. additionally, werecently showed that circadian transcription factors, circadian Loco-motor output cycles Kaput (cLocK) and brain and Muscle arnt-likeprotein-1 (bMaL1), bind to the HIV Ltr and increase HIV transcrip-tion. We hypothesised that circadian rhythms exert transcriptionalcontrol on latent HIV.HIV 1post-cART initiationA dynamic interplay of circulating extracellular vesicles and galectin-1 reprograms viral latency during HIV-1 infection